What are Polynucleotides?

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Polynucleotides are long chains of nucleotides - the building blocks of genetic material. They form the structural basis of DNA and RNA, the molecules responsible for storing and transmitting genetic information in living cells.

Each nucleotide contains:

• A nitrogenous base

• A sugar molecule

• A phosphate group

 

When linked together, these components form a polynucleotide chain that supports cellular repair, regeneration, and overall tissue health.

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How Polynucleotides Work in Aesthetic Medicine?

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In regenerative and aesthetic treatments, purified polynucleotides are injected into the skin to stimulate natural repair processes. Rather than simply adding volume like traditional fillers, polynucleotides:

• Stimulate fibroblast activity

• Support collagen and elastin production

• Improve skin elasticity and firmness

• Enhance hydration

• Reduce inflammation

• Promote tissue regeneration

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They work at a cellular level to improve overall skin quality, making them ideal for patients seeking natural-looking rejuvenation.

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Where Can Polynucleotides Be Injected?

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Polynucleotide treatments are versatile and can be used in multiple areas of the face and body.

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Facial Treatment Areas

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Under-Eye Area (Tear Trough)

• Improves dark circles

• Reduces crepey skin

• Enhances skin thickness

• Softens fine lines

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Cheeks

• Improves skin texture

• Boosts elasticity

• Restores radiance

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Perioral Area (Around the Mouth)

• Softens fine lines

• Improves skin firmness

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Forehead

• Smooths fine lines

• Enhances overall skin quality

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Neck & Décolletage

• Improves laxity

• Reduces fine lines

• Enhances hydration

 

Who Is Suitable for Polynucleotide Treatments?

 

Polynucleotide injections are suitable for individuals who:

• Have early signs of ageing

• Experience skin thinning

• Want subtle, natural rejuvenation

• Prefer regenerative treatments over volumising fillers

 

They are particularly effective for delicate areas such as the under-eye region, where traditional fillers may not always be suitable.

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Treatment & Results

• Minimal downtime

• Gradual, natural improvement

• Typically performed as a course of 2–3 sessions

• Results improve over several weeks as collagen production increases

 

Polynucleotides focus on improving skin health from within, delivering long-term skin quality enhancement rather than immediate volume change.

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